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[KO Validated] HK1 Rabbit Polyclonal Antibody (CAB1054)

SKU:
CAB1054
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • KO Validated Antibodies 1 Anti-HK1 Antibody CAB1054KO Validated
  • KO Validated Antibodies 1 Anti-HK1 Antibody CAB1054KO Validated
  • KO Validated Antibodies 1 Anti-HK1 Antibody CAB1054KO Validated
  • KO Validated Antibodies 1 Anti-HK1 Antibody CAB1054KO Validated
  • KO Validated Antibodies 1 Anti-HK1 Antibody CAB1054KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] HK1 Rabbit Polyclonal Antibody
SKU:CAB1054
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human HK1 (NP_000179.2).
Sequence:KIDK YLYA MRLS DETL IDIM TRFR KEMK NGLS RDFN PTAT VKML PTFV RSIP DGSE KGDF IALD LGGS SFRI LRVQ VNHE KNQN VHME SEVY DTPE NIVH GSGS QLFD HVAE CLGD FMEK RKIK DKKL PVGF TFSF PCQQ SKID EAIL ITWT KRFK ASGV EGAD VVKL LNKA IKKR GDYD ANIV AVVN DTVG TMMT CGY
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:HK; HKD; HKI; HXK1; NMSR; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; NEDVIBA; hexokinase; K1
Positive Sample:293T,MCF7,U-87MG,Mouse testis,Mouse brain,Mouse heart,Rat testis,Rat brain
Conjugate:Unconjugated
Cellular Localization:Mitochondrion outer membrane.
Calculated MW:102kDa
Observed MW:102kDa

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Purification Method:Affinity purification
Gene ID:3098
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] HK1 Rabbit pAb (CAB1054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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