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[KO Validated] HMGB1 Rabbit Polyclonal Antibody (CAB2553)

SKU:
CAB2553
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • KO Validated Antibodies 1 Anti-HMGB1 Antibody CAB2553KO Validated
  • KO Validated Antibodies 1 Anti-HMGB1 Antibody CAB2553KO Validated
  • KO Validated Antibodies 1 Anti-HMGB1 Antibody CAB2553KO Validated
  • KO Validated Antibodies 1 Anti-HMGB1 Antibody CAB2553KO Validated
  • KO Validated Antibodies 1 Anti-HMGB1 Antibody CAB2553KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] HMGB1 Rabbit Polyclonal Antibody
SKU:CAB2553
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 69-168 of human HMGB1 (NP_002119.1).
Sequence:ARYE REMK TYIP PKGE TKKK FKDP NAPK RPPS AFFL FCSE YRPK IKGE HPGL SIGD VAKK LGEM WNNT AADD KQPY EKKA AKLK EKYE KDIA AYRA KGKP
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:HMG1; HMG3; HMG-1; SBP-1; HMGB1
Positive Sample:293T,NIH/3T3,C6
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Chromosome, Cytoplasm, Endoplasmic reticulum-Golgi intermediate compartment, Endosome, Extracellular side, Nucleus, Peripheral membrane protein, Secreted.
Calculated MW:25kDa
Observed MW:29kDa

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Purification Method:Affinity purification
Gene ID:3146
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using HMGB1 Rabbit pAb (CAB2553) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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