Description
HOXD8 Transcription Factor Activity Assay
The HOXD8 Transcription Factor Activity Assay from Assay Genie is a cutting-edge kit designed for the detection and quantification of HOXD8 transcription factor activity in biological samples. This assay provides researchers with a reliable and accurate tool for studying the role of HOXD8 in gene regulation and cellular processes.HOXD8 is a key transcription factor that plays a critical role in controlling the expression of genes involved in development, differentiation, and disease. By measuring HOXD8 activity, researchers can gain valuable insights into its function and its impact on various biological pathways.
With its high sensitivity and specificity, the HOXD8 Transcription Factor Activity Assay delivers precise and reproducible results, allowing researchers to confidently investigate the role of HOXD8 in various physiological and pathological processes. This assay is a valuable tool for advancing our understanding of gene regulation and identifying potential therapeutic targets for a wide range of conditions.
| Product Name: | HOXD8 Transcription Factor Activity Assay |
| Product Code: | TFAB00128 |
| Target: | HOXD8 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie HOXD8 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | HOXD8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2q31.1 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
| UniProt Code: | P13378 |
| NCBI GenInfo Identifier: | 13124737 |
| NCBI Gene ID: | 3234 |
| NCBI Accession: | P13378.2 |
| UniProt Secondary Accession: | P13378,Q5BL00, Q8IXZ1, F8WBG7, |
| UniProt Related Accession: | P13378 |
| Molecular Weight: | 8,354 Da |
| NCBI Full Name: | Homeobox protein Hox-D8 |
| NCBI Synonym Full Names: | homeobox D8 |
| NCBI Official Symbol: | HOXD8 |
| NCBI Official Synonym Symbols: | HOX4; HOX4E; HOX5.4 |
| NCBI Protein Information: | homeobox protein Hox-D8 |
| UniProt Protein Name: | Homeobox protein Hox-D8 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-4E; Homeobox protein Hox-5.4 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXD8 |
