Description
Human HSF4 Recombinant Protein (N-GST)
Human HSF4 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Val171-Arg284, with an N-terminal GST tag. Predicted molecular weight: 38.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Heat shock factor protein 4 (HSF4) is a ~53 kDa protein. Heat-shock transcription factor that specifically binds heat shock promoter elements (HSE). For research use only.
Required for denucleation and organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light. In this process, may regulate denucleation of lens fiber cells in part by activating DNASE2B transcription. May be involved in DNA repair through the transcriptional regulation of RAD51. May up-regulate p53/TP53 protein in eye lens fiber cells, possibly through protein stabilization.
| Product Name: | Human HSF4 Recombinant Protein (N-GST) |
| SKU: | GXRP03065 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Heat shock factor protein 4, Heat shock transcription factor 4, HSF4, HSTF 4, HSF 4, hHSF4 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Val171-Arg284 |
| Calculated MW: | 38.93 kDa |
| UniProt: | Q9ULV5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
