Description
Human NPPA Recombinant Protein (N-GST)
Human NPPA Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Ala25-Arg123, with an N-terminal GST tag. Predicted molecular weight: 37.51 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Natriuretic peptides A (NPPA) is a ~16 kDa protein. Hormone that plays a key role in mediating cardio-renal homeostasis, and is involved in vascular remodeling and regulating energy metabolism. For research use only.
Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins, such as PRKG1, that drive various biological responses. Regulates vasodilation, natriuresis, diuresis and aldosterone synthesis and is therefore essential for regulating blood pressure, controlling the extracellular fluid volume and maintaining the fluid-electrolyte balance. Also involved in inhibiting cardiac remodeling and cardiac hypertrophy by inducing cardiomyocyte apoptosis and attenuating the growth of cardiomyocytes and fibroblasts. Plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus, and thus prevents pregnancy-induced hypertension.
| Product Name: | Human NPPA Recombinant Protein (N-GST) |
| SKU: | GXRP03362 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cardiodilatin, Pro atrial natriuretic factor 1-30, ANF 3-33, proANP, Atrial natriuretic factor prohormone, ANF 1-33, URO, LANH, proANP 31-67, Atrial natriuretic factor, Atrial natriuretic factor 8-33, VSDL, Atriopeptin I, CDD-ANF, ANF 8-33, Atrial natriuretic peptide prohormone, preproCDD-ANF, KP, CDD 95-126, Atrial natriuretic factor 3-33, Pro atrial natriuretic factor 99-126, Atrial natriuretic factor 1-33, proANP 95-126, proANF 99-126, proANF 79-98, Pro atrial natriuretic factor 31-67, ANP, Atriopeptin III, Alpha-hANP, Pro atrial natriuretic peptide 79-98, ANF, preproANP, Atriopeptin II, PND, Pro atrial natriuretic peptide 95-126, Natriuretic peptides A, Pro atrial natriuretic peptide 1-30, CDD-ANP (95-126), proANP 79-98, Pro atrial natriuretic factor 79-98, Atriopeptigen, proANF, CDD, proANF 1-30, LANP, CDD-ANP (99-126), Pro atrial natriuretic peptide 31-67, NPPA, Alpha-atrial natriuretic peptide, proANF 31-67, Cardionatrin, Long-acting natriuretic hormone, proANP 1-30 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Ala25-Arg123 |
| Calculated MW: | 37.51 kDa |
| UniProt: | P01160 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
