Description
Human MAPK7 Recombinant Protein (N-GST)
Human MAPK7 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Val560-Glu793, with an N-terminal GST tag. Predicted molecular weight: 50.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mitogen-activated protein kinase 7 (MAPK7) is a ~88 kDa protein. Plays a role in various cellular processes such as proliferation, differentiation and cell survival. For research use only.
The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via interaction with STUB1/CHIP and promotion of STUB1-mediated ubiquitination and degradation of ICER-type isoforms of CREM.
| Product Name: | Human MAPK7 Recombinant Protein (N-GST) |
| SKU: | GXRP02167 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MAP kinase 7, Extracellular signal-regulated kinase 5, PRKM7, BMK1, Big MAP kinase 1, BMK-1, ERK-5, ERK5, Mitogen-activated protein kinase 7, MAPK7, MAPK 7 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Val560-Glu793 |
| Calculated MW: | 50.19 kDa |
| UniProt: | Q13164 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
