Description
Human CD63 Recombinant Protein (N-GST)
Human CD63 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Ala103-Val203, with an N-terminal GST tag. Predicted molecular weight: 38.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CD63 antigen (LAMP3) is a ~25 kDa protein. Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. For research use only.
Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes.
| Product Name: | Human CD63 Recombinant Protein (N-GST) |
| SKU: | GXRP00754 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Ocular melanoma-associated antigen, TSPAN30, CD63 antigen, LAMP-3, Tetraspanin-30, OMA81H, Lysosomal-associated membrane protein 3, Tspan-30, Granulophysin, MLA1, Melanoma-associated antigen ME491, CD63 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Ala103-Val203 |
| Calculated MW: | 38.35 kDa |
| UniProt: | P08962 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
