Description
Human NPR1 Recombinant Protein (C-Strep)
Human NPR1 Recombinant Protein (C-Strep) is a recombinant protein expressed in mammalian cells, spanning Met1-Glu473, with a C-terminal Strep tag. Predicted molecular weight: 53.58 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Atrial natriuretic peptide receptor 1 is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. For research use only.
Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.
| Product Name: | Human NPR1 Recombinant Protein (C-Strep) |
| SKU: | GXRP09074 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Atrial natriuretic peptide receptor 1, EC:4.6.1.2, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, NPR1, ANPRA |
| Tag: | C-Strep |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Glu473 |
| Calculated MW: | 53.58 kDa |
| UniProt: | P16066 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >95% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
