Description
Human Periodontal Disease Array (20 targets) (SARB0061)
The Human Periodontal Disease Array (SARB0061) is a cutting-edge tool for researchers studying periodontal diseases and related conditions. This array contains 20 unique targets, allowing for comprehensive analysis of key molecules involved in periodontal disease pathology.With the Human Periodontal Disease Array, researchers can simultaneously measure the expression levels of multiple biomarkers, including inflammatory cytokines, growth factors, and matrix metalloproteinases. This comprehensive approach provides valuable insights into the complex molecular mechanisms underlying periodontal disease progression and can help identify potential therapeutic targets.Designed for use with human samples, this array is a powerful tool for studying the molecular signatures of periodontal disease in patient samples.
By identifying specific biomarker profiles associated with disease severity or treatment response, researchers can improve diagnostic accuracy and develop more effective personalized treatment strategies for patients with periodontal diseases.Overall, the Human Periodontal Disease Array offers a cost-effective and efficient solution for researchers seeking to gain a deeper understanding of the molecular pathways involved in periodontal diseases. Whether investigating novel biomarkers, exploring new therapeutic targets, or monitoring treatment responses, this array is a valuable resource for advancing research in the field of periodontal disease.
| Product Sku: | SARB0061 |
| Size: | 2, 4, or 8 |
| Species Detected: | Human |
| Number of Targets Detected: | 20 |
| Gene Symbols: | CCL3, CRP, CXCL8, GPNMB, IFNG, IL10, IL12A, IL17A, IL1A, IL1B|IL2, IL4, IL6, MMP13, MMP9, SPP1, TGFB1, TNF, TNFRSF11A, TNFRSF11B |
| Compatible Sample Types: | Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Lysates |
| Design Principle: | Sandwich-based |
| Method of Detection: | Chemiluminescence |
| Pathway: | |
| Quantitative/Semi-Quantitative: | Semi-Quantitative |
| Solid Support: | Membrane |
| Suggested Application(s): | Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process |
| Storage/Stability: | For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period. Once thawed, store array membranes and 1X Blocking Buffer at -20°C and all other reagents undiluted at 4°C for no more than 3 months. |
| Hover over target for more information | ||||
|---|---|---|---|---|
IL-1 alpha (IL-1 F1)
| IL-1 beta (IL-1 F2)
| IL-2
| IL-4
| IL-6
|
IL-8 (CXCL8)
| IL-10
| IL-12 p70
| IFN-gamma
| TGF beta 1
|
TNF alpha
| Osteoprotegerin (TNFRSF11B)
| IL-17A
| MIP-1 alpha (CCL3)
| MMP-13
|
MMP-9
| Osteopontin (SPP1)
| RANK (TNFRSF11A)
| CRP (C-Reactive Protein)
| Osteoactivin (GPNMB)
|
- Easy to use
- No specialized equipment needed
- Compatible with nearly any liquid sample
- Proven technology
- Highly sensitive (pg/ml)
- Sandwich ELISA specificity
- Higher density than ELISA, Western blot or bead-based multiplex
- Human Periodontal Disease Array C1 Membranes
- Blocking Buffer
- Wash Buffer 1
- Wash Buffer 2
- Biotinylated Detection Antibody Cocktail
- Streptavidin-Conjugated HRP
- Detection Buffer C
- Detection Buffer D
- Lysis Buffer
- 8-Well Incubation Tray
- Plastic Sheets
- Array Templates
Other Materials Required
- Pipettors, pipet tips and other common lab consumables
- Orbital shaker or oscillating rocker
- Tissue Paper, blotting paper or chromatography paper
- Adhesive tape or Saran Wrap
- Distilled or de-ionized water
- A chemiluminescent blot documentation system , X-ray Film and a suitable film processor, or another chemiluminescent detection system.
| 1. | Block membranes |
| 2. | Incubate with Sample |
| 3. | Incubate with Biotinylated Detection Antibody Cocktail |
| 4. | Incubate with HRP-Conjugated Streptavidin |
| 5. | Incubate with Detection Buffers |
| 6. | Image with chemiluminescent imaging system |
| 7. | Perform densitometry and analysis |
