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[KO Validated] GDI2 Rabbit Polyclonal Antibody (CAB8615)

SKU:
CAB8615
Product Type:
Antibody
Applications:
WB
IF
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
  • KO Validated Antibodies 1 Anti-GDI2 Antibody CAB8615KO Validated
  • KO Validated Antibodies 1 Anti-GDI2 Antibody CAB8615KO Validated
  • KO Validated Antibodies 1 Anti-GDI2 Antibody CAB8615KO Validated
€139 - €419
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Description

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Product Name:[KO Validated] GDI2 Rabbit Polyclonal Antibody
SKU:CAB8615
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 296-445 of human GDI2 (NP_001485.2).
Sequence:QVIR VICI LSHP IKNT NDAN SCQI IIPQ NQVN RKSD IYVC MISF AHNV AAQG KYIA IVST TVET KEPE KEIR PALE LLEP IEQK FVSI SDLL VPKD LGTE SQIF ISRT YDAT THFE TTCD DIKN IYKR MTGS EFDF EEMK RKKN DIYG ED
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:200 - 1:3000 IF/ICC,1:50 - 1:100
Synonyms:RABGDIB; HEL-S-46e; I2
Positive Sample:HT-29,A-549,HepG2,U-87MG,Mouse spleen,Mouse kidney,Mouse lung,Rat liver,Rat spinal cord
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Membrane, Peripheral membrane protein.
Calculated MW:51kDa
Observed MW:51kDa

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Purification Method:Affinity purification
Gene ID:2665
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using GDI2 antibody (CAB8615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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