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[KO Validated] HADHA Rabbit Polyclonal Antibody (CAB5346)

SKU:
CAB5346
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • KO Validated Antibodies 1 Anti-HADHA Antibody CAB5346KO Validated
  • KO Validated Antibodies 1 Anti-HADHA Antibody CAB5346KO Validated
  • KO Validated Antibodies 1 Anti-HADHA Antibody CAB5346KO Validated
  • KO Validated Antibodies 1 Anti-HADHA Antibody CAB5346KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] HADHA Rabbit Polyclonal Antibody
SKU:CAB5346
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 484-763 of human HADHA (NP_000173.2).
Sequence:IAAV SKRP EKVI GMHY FSPV DKMQ LLEI ITTE KTSK DTSA SAVA VGLK QGKV IIVV KDGP GFYT TRCL APMM SEVI RILQ EGVD PKKL DSLT TSFG FPVG AATL VDEV GVDV AKHV AEDL GKVF GERF GGGN PELL TQMV SKGF LGRK SGKG FYIY QEGV KRKD LNSD MDSI LASL KLPP KSEV SSDE DIQF RLVT RFVN EAVM CLQE GILA TPAE GDIG AVFG LGFP PCLG GPFR FVDL YGAQ KIVD RLKK YEAA YGKQ FTPC QLLA DHAN SPNK KFYQ
Tested Applications:WB IF/ICC IP ELISA
Recommended Dilution:WB,1:2000 - 1:6000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:GBP; ECHA; HADH; LCEH; MTPA; LCHAD; TP-ALPHA; HA
Positive Sample:293T,K-562
Conjugate:Unconjugated
Cellular Localization:Mitochondrion.
Calculated MW:83kDa
Observed MW:78kDa

This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Purification Method:Affinity purification
Gene ID:3030
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from K-562 cells, using [KO Validated] HADHA Rabbit pAb (CAB5346) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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