The PDCD4 Polyclonal Antibody (CAB2570) is a vital tool for research involving PDCD4, a protein involved in cell growth and proliferation regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for Western blot applications. By targeting the PDCD4 protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for studies in molecular biology and cancer research.PDCD4, also known as programmed cell death protein 4, is a tumor suppressor that plays a crucial role in controlling cell cycle progression and apoptosis.
Dysregulation of PDCD4 has been implicated in various cancers and other diseases, highlighting its importance in cellular processes. By studying the function of PDCD4, researchers can gain valuable insights into potential therapeutic targets for cancer and other related disorders.Overall, the PDCD4 Polyclonal Antibody (CAB2570) is a valuable tool for scientists seeking to explore the roles and mechanisms of PDCD4 in cellular processes and disease, providing a foundation for further research and the development of potential treatment strategies.
Product Name:
[KO Validated] PDCD4 Rabbit Polyclonal Antibody
SKU:
CAB2570
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_055271.2).
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] PDCD4 Rabbit pAb (CAB2570) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
