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[KO Validated] SQSTM1/p62 Rabbit Monoclonal Antibody (CAB19700)

SKU:
CAB19700
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
  • KO Validated Antibodies 2 Anti-SQSTM1 / p62 Antibody KO Validated CAB19700
  • KO Validated Antibodies 2 Anti-SQSTM1 / p62 Antibody KO Validated CAB19700
  • KO Validated Antibodies 2 Anti-SQSTM1 / p62 Antibody KO Validated CAB19700
  • KO Validated Antibodies 2 Anti-SQSTM1 / p62 Antibody KO Validated CAB19700
  • KO Validated Antibodies 2 Anti-SQSTM1 / p62 Antibody KO Validated CAB19700
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] SQSTM1/p62 Rabbit Monoclonal Antibody
SKU:CAB19700
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 341-440 of human SQSTM1/p62 (Q13501).
Sequence:LSSK EVDP STGE LQSL QMPE SEGP SSLD PSQE GPTG LKEA ALYP HLPP EADP RLIE SLSQ MLSM GFSD EGGW LTRL LQTK NYDI GAAL DTIQ YSKH PPPL
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3; SQSTM1/p62
Positive Sample:293T,HeLa,L929,C2C12,PC-12
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome.
Calculated MW:48kDa
Observed MW:62kDa

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Purification Method:Affinity purification
Gene ID:8878
Clone Number:ARC0180
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SQSTM1/p62 Rabbit mAb (CAB19700) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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