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[KO Validated] SQSTM1/p62 Rabbit Polyclonal Antibody (CAB11483)

SKU:
CAB11483
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • KO Validated Antibodies 1 Anti-SQSTM1 / p62 Antibody CAB11483KO Validated
  • KO Validated Antibodies 1 Anti-SQSTM1 / p62 Antibody CAB11483KO Validated
  • KO Validated Antibodies 1 Anti-SQSTM1 / p62 Antibody CAB11483KO Validated
  • KO Validated Antibodies 1 Anti-SQSTM1 / p62 Antibody CAB11483KO Validated
  • KO Validated Antibodies 1 Anti-SQSTM1 / p62 Antibody CAB11483KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] SQSTM1/p62 Rabbit Polyclonal Antibody
SKU:CAB11483
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-356 of human SQSTM1/p62 (NP_001135770.1).
Sequence:MAMS YVKD DIFR IYIK EKKE CRRD HRPP CAQE APRN MVHP NVIC DGCN GPVV GTRY KCSV CPDY DLCS VCEG KGLH RGHT KLAF PSPF GHLS EGFS HSRW LRKV KHGH FGWP GWEM GPPG NWSP RPPR AGEA RPGP TAES ASGP SEDP SVNF LKNV GESV AAAL SPLG IEVD IDVE HGGK RSRL TPVS PESS STEE KSSS QPSS CCSD PSKP GGNV EGAT QSLA EQMR KIAL ESEG RPEE QMES DNCS GGDD DWTH LSSK EVDP STGE LQSL QMPE SEGP SSLD PSQE GPTG LKEA ALYP HLPP EADP RLIE SLSQ MLSM GFSD EGGW LTRL LQTK NYDI GAAL DTIQ YSKH PPPL
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3; SQSTM1/p62
Positive Sample:293T,HeLa
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome.
Calculated MW:48kDa
Observed MW:62kDa

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Purification Method:Affinity purification
Gene ID:8878
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SQSTM1/p62 Rabbit pAb (CAB11483) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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