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GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1280)

Datasheet MSDS
SKU AGEL1280
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Reactivity Mouse
Applications FC
$124 - $454

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Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (AF647 Conjugated, IM7) is a versatile tool for researchers studying CD44 expression in both mouse and human samples. This monoclonal antibody, conjugated with AF647 for enhanced detection capabilities, targets the CD44 protein which is involved in cell adhesion, migration, and signaling.CD44 is a transmembrane glycoprotein that is known to play a key role in cell-cell interactions, cell adhesion, and cell migration processes. Its expression has been associated with various physiological and pathological conditions including cancer metastasis, inflammation, and stem cell homing. The IM7 monoclonal antibody recognizes CD44 across species, making it suitable for a wide range of applications in immunofluorescence, flow cytometry, and immunohistochemistry.

By utilizing the Mouse/Human CD44 Monoclonal Antibody (AF647 Conjugated, IM7), researchers can delve deeper into the functions of CD44 in different biological contexts, gaining valuable insights into its role in disease progression and potential therapeutic targets. This antibody represents a valuable tool for studies in immunology, oncology, and regenerative medicine, providing researchers with a reliable reagent for accurate detection and analysis of CD44 expression in experimental systems.

Product Title:GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1280
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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