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Purified Anti-Human/Mouse CD44 Antibody [IM7] (AGEL0364)

Datasheet MSDS
SKU AGEL0364
Product Type Antibody
Antibody Type Monoclonal Antibody
Host Species Rat
Isotype IgG2b
Clone IM7
Conjugation Unconjugated
Applications FC
Applications IHC
Applications IP
$33 - $83

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Description

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Purified Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse/Human CD44 Monoclonal Antibody (IM7-AGEL0364) offered by AssayGenie is a cutting-edge tool designed for researchers delving into the intricate world of CD44, a multifunctional cell surface glycoprotein involved in numerous biological processes. This monoclonal antibody, engineered for use in both mouse and human samples, exhibits a high level of specificity and sensitivity, making it an invaluable asset in a variety of experimental settings.The IM7-AGEL0364 antibody is meticulously crafted to target the CD44 protein, facilitating precise detection and analysis across different cell types. By binding specifically to CD44, researchers can gain deeper insights into the roles and functions of this pivotal molecule in cellular adhesion, migration, and signaling pathways. Whether exploring stem cell biology, cancer metastasis, or immune system regulation, this antibody is a versatile tool that can elevate the quality and accuracy of your research outcomes.

In the realm of scientific investigation, the CD44 molecule holds great significance due to its involvement in processes such as cell proliferation, differentiation, and tissue repair. Its aberrant expression has been linked to various disease states, including cancer, inflammation, and metastasis, underscoring the importance of unraveling its mechanisms of action. With the IM7-AGEL0364 antibody at your disposal, you are equipped to delve deep into the intricate functions of CD44, paving the way for novel insights and potential therapeutic discoveries in the realms of oncology, immunology, and beyond.

Product Title:Purified Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL0364
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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