Biotin Anti-Human/Mouse CD44 Antibody [IM7] (AGEL0365)
- SKU:
- AGEL0365
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Host Species:
- Rat
- Isotype:
- IgG2b
- Clone:
- IM7
- Conjugation:
- Biotin
- Applications:
- FC
Frequently bought together:
Description
Product Title: | Biotin Anti-Human/Mouse CD44 Antibody [IM7] |
SKU: | AGEL0365 |
Size: | 25µg, 100µg |
Clone No: | IM7 |
Synonyms: | CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4; |
Host Species: | Rat |
Reactivity: | Human;Mouse |
Application: | FCM |
Isotype: | Rat IgG2b, κ |
Isotype Control: | Biotin Rat IgG2b, κ Isotype Control[LTF-2] |
Form: | Liquid |
Conjugation: | Biotin |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P15379 P16070 |
Gene ID: | 12505,960 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation. |