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APC Anti-Human/Mouse CD44 Antibody [IM7] (AGEL0367)

Datasheet MSDS
SKU AGEL0367
Product Type Antibody
Antibody Type Monoclonal Antibody
Host Species Rat
Isotype IgG2b
Clone IM7
Conjugation APC
Applications FC
$66 - $264

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Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse Human CD44 Monoclonal Antibody (APC Conjugated) (IM7-AGEL0367) is a versatile tool for researchers working with CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling processes. This monoclonal antibody, conjugated with allophycocyanin (APC), offers high specificity and sensitivity in detecting CD44 in both mouse and human samples.CD44 is a multifunctional molecule with diverse roles in various physiological and pathological processes, including immune responses, inflammation, and cancer progression. By targeting CD44, researchers can gain insights into its function and potential as a therapeutic target in diseases such as cancer, inflammation, and metastasis.

The IM7-AGEL0367 antibody is well-suited for flow cytometry and immunofluorescence applications, allowing for precise identification and characterization of CD44-expressing cells in complex biological samples. Its reliable performance and cross-reactivity with both mouse and human CD44 make it a valuable tool for investigations in immunology, oncology, and stem cell research.By utilizing the APC-conjugated CD44 antibody, researchers can advance their understanding of CD44-mediated biological processes, paving the way for innovative approaches to diagnostics and therapeutic interventions in a variety of pathological conditions.

Product Title:APC Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL0367
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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