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APC Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1283)

Datasheet MSDS
SKU AGEL1283
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone IM7
Conjugation APC
€38 - €113

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Description

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APC Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse-Human CD44 Monoclonal Antibody (APC Conjugated, IM7) offered by Assay Genie (Part No: AGEL1283) is a cutting-edge tool for researchers delving into the realms of immunology and cell biology. This highly specific antibody targets the CD44 protein, a multifunctional cell surface receptor involved in cell adhesion, migration, and signaling pathways.With its unique dual reactivity to mouse and human samples, this monoclonal antibody provides versatility for a wide range of experimental studies. The APC conjugation enhances the detection sensitivity, making it ideal for flow cytometry and immunofluorescence applications. Validated for use in various experimental techniques, including cell staining and sorting, this antibody facilitates precise identification and analysis of CD44-expressing cells in both research and clinical settings.

CD44 is a key player in numerous physiological and pathological processes, such as immune response modulation, tissue regeneration, and cancer progression. By targeting CD44 with this specific antibody, researchers can uncover new insights into the role of this protein in various diseases and physiological functions, paving the way for innovative therapeutic approaches and biomarker discovery.Equip your research endeavors with the Mouse-Human CD44 Monoclonal Antibody (APC Conjugated, IM7) from Assay Genie and unlock the potential for groundbreaking discoveries in cell biology and immunology.

Product Title:APC Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1283
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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