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[KO Validated] NOX4 Rabbit Polyclonal Antibody (CAB11274)

SKU:
CAB11274
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • KO Validated Antibodies 1 Anti-NOX4 Antibody CAB11274KO Validated
  • KO Validated Antibodies 1 Anti-NOX4 Antibody CAB11274KO Validated
  • KO Validated Antibodies 1 Anti-NOX4 Antibody CAB11274KO Validated
  • KO Validated Antibodies 1 Anti-NOX4 Antibody CAB11274KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] NOX4 Rabbit Polyclonal Antibody
SKU:CAB11274
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 328-578 of human NADPH oxidase 4 (NOX4) (NP_058627.1).
Sequence:KENF KARP GQYI TLHC PSVS ALEN HPFT LTMC PTET KATF GVHL KIVG DWTE RFRD LLLP PSSQ DSEI LPFI QSRN YPKL YIDG PFGS PFEE SLNY EVSL CVAG GIGV TPFA SILN TLLD DWKP YKLR RLYF IWVC RDIQ SFRW FADL LCML HNKF WQEN RPDY VNIQ LYLS QTDG IQKI IGEK YHAL NSRL FIGR PRWK LLFD EIAK YNRG KTVG VFCC GPNS LSKT LHKL SNQN NSYG TRFE YNKE SFS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:KOX; KOX-1; RENOX; 4)
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus, focal adhesion, nucleolus.
Calculated MW:67kDa
Observed MW:65kDa

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:50507
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using [KO Validated] NADPH oxidase 4 (NOX4) Rabbit pAb (CAB11274) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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