null

Anti-NDUFS3 Antibody (CAB4602)

SKU:
CAB4602
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CI-30
Research Area:
Cell Biology
  • Cell Biology Antibodies 17 Anti-NDUFS3 Antibody CAB4602
  • Cell Biology Antibodies 17 Anti-NDUFS3 Antibody CAB4602
€139 - €419
Frequently bought together:

Description

Product Name:NDUFS3 Rabbit mAb
Product Code:CAB4602
Size:20uL, 50uL, 100uL
Synonyms:CI-30
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human NDUFS3
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, A-431, SH-SY5Y
Immunogen:A synthesized peptide derived from human NDUFS3
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4722
Uniprot:O75489
Calculated MW:30kDa
Observed MW:28KDa
UniProt Protein Function:NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family.
UniProt Protein Details:

Protein type:EC 1.6.5.3; Oxidoreductase; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial

Chromosomal Location of Human Ortholog: 11p11.11

Cellular Component: mitochondrial matrix; mitochondrial membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleus

Molecular Function:NADH dehydrogenase activity; protein binding

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; negative regulation of cell growth; substantia nigra development

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

NCBI Summary:This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]
UniProt Code:O75489
NCBI GenInfo Identifier:6166589
NCBI Gene ID:4722
NCBI Accession:O75489.1
UniProt Secondary Accession:O75489,Q9UNQ8, B2R9J1, B4DFM8,
UniProt Related Accession:O75489
Molecular Weight:14,679 Da
NCBI Full Name:NADH dehydrogenase
NCBI Synonym Full Names:NADH:ubiquinone oxidoreductase core subunit S3
NCBI Official Symbol:NDUFS3  
NCBI Official Synonym Symbols:CI-30  
NCBI Protein Information:NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
UniProt Protein Name:NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
UniProt Synonym Protein Names:Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit
UniProt Gene Name:NDUFS3  
UniProt Entry Name:NDUS3_HUMAN

Related Products