OPA1 Rabbit Polyclonal Antibody (CAB9833)
- SKU:
- CAB9833
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | OPA1 Rabbit Polyclonal Antibody |
SKU: | CAB9833 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-600 of human OPA1 (NP_056375.2). |
Sequence: | SESD KHFR KVSD KEKI DQLQ EELL HTQL KYQR ILER LEKE NKEL RKLV LQKD DKGI HHRK LKKS LIDM YSEV LDVL SDYD ASYN TQDH LPRV VVVG DQSA GKTS VLEM IAQA RIFP RGSG EMMT RSPV KVTL SEGP HHVA LFKD SSRE FDLT KEED LAAL RHEI ELRM RKNV KEGC TVSP ETIS LNVK GPGL QRMV LVDL PGVI NTVT SGMA PDTK ETIF SISK AYMQ NPNA IILC IQDG SVDA ERSI VTDL VSQM DPHG RRTI FVLT KVDL AEKN VASP SRIQ QIIE GKLF PMKA LGYF AVVT GKGN SSES IEAI REYE EEFF QNSK LLKT SMLK AHQV TTRN LSLA VSDC FWKM VRES VEQQ ADSF KATR FNLE TEWK NNYP RLRE LDRN ELFE KAKN E |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:2000 - 1:8000 IF/ICC,1:50 - 1:200 |
Synonyms: | NPG; NTG; MGM1; BERHS; largeG; MTDPS14; OPA1 |
Positive Sample: | A-431,Mouse heart,Mouse brain,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Mitochondrion intermembrane space, Single-pass membrane protein. |
Calculated MW: | 112kDa |
Observed MW: | 80-100kDa |
The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.
Purification Method: | Affinity purification |
Gene ID: | 4976 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |