Anti-P2Y purinoceptor 14 Antibody (CAB8178)

Antibody Name:	P2RY14 Rabbit Polyclonal Antibody
Antibody SKU:	CAB8178
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 209-338 of human P2RY14 (NP_055694.3).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	Jurkat, U-937, SH-SY5Y, MCF7, Mouse spleen, Mouse lung, Mouse heart, Rat spleen, Rat lung

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 209-338 of human P2RY14 (NP_055694.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	ITKK IFKS HLKS SRNS TSVK KKSS RNIF SIVF VFFV CFVP YHIA RIPY TKSQ TEAH YSCQ SKEI LRYM KEFT LLLS AANV CLDP IIYF FLCQ PFRE ILCK KLHI PLKA QNDL DISR IKRG NTTL ESTD TL
Gene ID:	9934
Uniprot:	Q15391
Cellular Location:	Cell membrane, Multi-pass membrane protein
Calculated MW:	38kDa
Observed MW:	42kDa

Synonyms:

P2RY14, BPR105, GPR105, P2Y14

Background:

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

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UniProt Code:	Q15391
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UniProt Secondary Accession:	Q15391
UniProt Related Accession:	Q15391
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	Western blot analysis of extracts of various cell lines, using P2RY14 antibody (CAB8178) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded rat ovary using P2RY14 Rabbit pAb (CAB8178) at dilution of 1:200 (40x lens).

Antibodies

P2RY14 Antibody (PACO00861)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)