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Anti-PLSCR3 Antibody (CAB12371)

SKU:
CAB12371
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-PLSCR3 Antibody CAB12371
  • Cell Death Antibodies 1 Anti-PLSCR3 Antibody CAB12371
€139 - €419
Frequently bought together:

Description

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Antibody Name:Anti-PLSCR3 Antibody
Antibody SKU:CAB12371
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human PLSCR3 (NP_065093.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, 293T, HepG2, BxPC-3, HeLa, Mouse brain, Mouse heart, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human PLSCR3 (NP_065093.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAGY LPPK GYAP SPPP PYPV TPGY PEPA LHPG PGQA PVPA QVPA PAPG FALF PSPG PVAL GSAA PFLP LPGV PSGL EFLV QIDQ ILIH QKAE RVET FLGW ETCN RYEL RSGA GQPL GQAA EESN CCAR LCCG ARRP LRVR LADP GDRE VLRL LRPL HCGC SCCP CGLQ EMEV QAPP GTTI GHVL QTWH PFLP KFSI QDAD RQTV LRVV GPCW TCGC GTDT NFEV KTRD ESRS VGRI SKQW GGLV REAL TDAD DFGL QFPL DLDV RVKA VLLG ATFL IDYM FFEK RGGA GPSA VTS
Gene ID:57048
Uniprot:Q9NRY6
Cellular Location:Mitochondrion membrane, Single-pass type II membrane protein
Calculated MW:31kDa
Observed MW:32kDa
Synonyms:PLSCR3
Background:
UniProt Protein Function:PLSCR3: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: mitochondrion; plasma membrane

Molecular Function:calcium-dependent protein binding; phospholipid scramblase activity; protein binding

UniProt Code:Q9NRY6
NCBI GenInfo Identifier:296452876
NCBI Gene ID:57048
NCBI Accession:Q9NRY6.2
UniProt Secondary Accession:Q9NRY6,Q567U0, Q8NBW6, Q96F13, A8K252,
UniProt Related Accession:Q9NRY6
Molecular Weight:32kDa
NCBI Full Name:Phospholipid scramblase 3
NCBI Synonym Full Names:phospholipid scramblase 3
NCBI Official Symbol:PLSCR3  
NCBI Protein Information:phospholipid scramblase 3
UniProt Protein Name:Phospholipid scramblase 3
UniProt Synonym Protein Names:Ca(2+)-dependent phospholipid scramblase 3
Protein Family:Phospholipid scramblase
UniProt Gene Name:PLSCR3  
Anti-PLSCR3 Antibody (CAB12371)Western blot analysis of extracts of various cell lines, using PLSCR3 antibody (CAB12371) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-PLSCR3 Antibody (CAB12371)Immunofluorescence analysis of C6 cells using PLSCR3 Polyclonal Antibody (CAB12371) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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