The PP2A-B56gamma/PR61gamma/PPP2R5C Antibody (CAB5480) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blotting applications. By binding specifically to the PPP2R5C protein, this antibody enables the detection and analysis of PPP2R5C levels in various cell types, providing valuable insights for studies in cell biology and cancer research.PPP2R5C is a key player in the control of cell cycle progression and cell proliferation, making it a potential target for therapeutic interventions in cancer and other proliferative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PP2A-B56gamma/PR61gamma/PPP2R5C Antibody
SKU:
CAB5480
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
B56G, PR61G, B56gamma, PP2A-B56γ/PR61γ/PPP2R5C
Positive Sample:
MCF7, K-562, Mouse testis
Cellular Localization:
Chromosome, Nucleus, Centromere.
Calculated MW:
61kDa
Observed MW:
68-71kDa
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method
Affinity purification
Gene ID
5527
RRID
AB_2766281
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PP2A-B56γ/PR61γ/PPP2R5C Rabbit pAb (CAB5480) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
