The Recombinant Lamin B2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321385) against Lamin B2. Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC and IP applications. It has been validated by WB analysis of HeLa, HepG2, IHC analysis of Human bladder cancer and IP analysis of HeLa cells extracts. The target is localized to the nucleus.