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Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody (AGEL7003)

Datasheet MSDS
SKU AGEL7003
Product Type Antibody
Reactivity Human
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C331698
Conjugate Unconjugated
$606 - $843

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Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody

The Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331698) against PTP1B (Ser352). PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of Jurkat. The target is localized to the endoplasmic reticulum membrane.

Product Name:Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody
SKU:AGEL7003
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:PTP1B, PTPN, PTPN1
Reactivity:Human
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser352 of human PTP1B
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C331698
Host:Rabbit
Isotype:Rabbit IgG
Target:PTP1B (Ser352)
Conjugation:Unconjugated
Observed MW:50 kDa
Calculated MW:50 kDa
Recommended Dilution:WB 1:1000-5000
UniProt:P18031
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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