The Recombinant Phospho-PTP1B (Ser378) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331702) against PTP1B (Ser378). Protein tyrosine phosphatase 1B (PTPN1) is a non-transmembrane protein tyrosine phosphatase, which is located on the face of the endoplasmic reticulum, and serves a critical role in regulating the activities of major signaling pathways involved in different diseases, including obesity, diabetes and cancer. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HeLa. The target is localized to the membrane.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Phospho-PTP1B (Ser378) Monoclonal Antibody at dilution of 1:1000. (-): HeLa, (2): HeLa+ Okadaic A+ calyculin A (100 nM, 60 min) Observed-MW:50 kDa Calculated-MW:50 kDa