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Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody (AGEL6571)

Datasheet MSDS
SKU AGEL6571
Product Type Antibody
Reactivity Human
Applications WB, IF
Host Species Rabbit
Clonality Monoclonal
Clone C371266
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody

The Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C371266) against PTP1B (Ser386). Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB and IF applications. It has been validated by WB analysis of 293T, Jurkat and IF analysis of HeLa, SW480. The target is localized to the endoplasmic reticulum.

Product Name:Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody
SKU:AGEL6571
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:PTP1B, PTPN, PTPN1
Reactivity:Human
Immunogen:Recombinant human Phospho-PTP1B (Ser386) fragment
Applications:WBIF
Clonality:Recombinant Monoclonal
Clone No:C371266
Host:Rabbit
Isotype:Rabbit IgG
Target:PTP1B (Ser386)
Conjugation:Unconjugated
Observed MW:50 kDa
Calculated MW:50 kDa
Recommended Dilution:WB 1:500-2000; IF 1:50
UniProt:P18031
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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