The Recombinant XIAP Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170326) against XIAP. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IF and ELISA applications. It has been validated by WB analysis of 3T3-L1. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant XIAP Monoclonal Antibody
SKU:
AGEL5645
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
API, API3, Baculoviral IAP repeat-containing protein, Baculoviral IAP repeat-containing protein 4, BIRC, BIRC4, E3 ubiquitin-protein ligase XIAP, hIAP-3, hIAP3, IAP, IAP-3, IAP-like protein, IAP3, ILP, ILP1, Inhibitor of apoptosis protein, Inhibitor of apoptosis protein 3, MIHA, RING-type E3 ubiquitin transferase XIAP, X-linked inhibitor of apoptosis, X-linked inhibitor of apoptosis protein, XIAP, XLP, XLP2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human XIAP protein
Applications:
WBIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C170326
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
XIAP
Conjugation:
Unconjugated
Observed MW:
57 kDa
Calculated MW:
57 kDa
Recommended Dilution:
WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P98170
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.