Description
RREB1 Transcription Factor Activity Assay
The Rreb1 Transcription Factor Activity Assay kit is a powerful tool for researchers studying gene expression regulation. This kit allows for the sensitive and accurate detection of Rreb1 transcription factor activity in various biological samples, including cell lysates and tissue extracts.Rreb1 is a key transcription factor that plays a critical role in regulating gene expression, affecting a wide range of cellular processes. Dysregulation of Rreb1 activity has been implicated in various diseases, making it an important target for further investigation.
With high sensitivity and specificity, this assay kit provides reliable and reproducible results, enabling researchers to gain valuable insights into the mechanisms underlying gene expression regulation. Whether studying developmental processes, disease pathways, or potential therapeutic targets, the Rreb1 Transcription Factor Activity Assay kit is an essential tool for research in molecular biology and beyond.
| Product Name: | RREB1 Transcription Factor Activity Assay |
| Product Code: | TFAB00155 |
| Target: | RREB1 |
| Reactivity: | Human |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie RREB1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1. |
| NCBI Summary: | The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q92766 |
| NCBI GenInfo Identifier: | 152031673 |
| NCBI Gene ID: | 6239 |
| NCBI Accession: | Q92766.3 |
| UniProt Secondary Accession: | Q92766,O75567, O75568, Q5VYB2, Q6BEP5, Q6BEP6, Q6BEP8 Q86SU2, Q9Y474, A2RRF5, E2GM80, E2GM81, |
| UniProt Related Accession: | Q92766 |
| Molecular Weight: | 34,614 Da |
| NCBI Full Name: | Ras-responsive element-binding protein 1 |
| NCBI Synonym Full Names: | ras responsive element binding protein 1 |
| NCBI Official Symbol: | RREB1 |
| NCBI Official Synonym Symbols: | HNT; FINB; LZ321; Zep-1; RREB-1 |
| NCBI Protein Information: | ras-responsive element-binding protein 1 |
| UniProt Protein Name: | Ras-responsive element-binding protein 1 |
| UniProt Synonym Protein Names: | Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Zinc finger motif enhancer-binding protein 1; Zep-1 |
| Protein Family: | Ras-responsive element-binding protein |
| UniProt Gene Name: | RREB1 |
| UniProt Entry Name: | RREB1_HUMAN |
