Anti-SAM68 Antibody (CAB3886)

Antibody Name:	Anti-SAM68 Antibody
Antibody SKU:	CAB3886
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human SAM68

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	HeLa, HepG2, NIH/3T3, Jurkat, Rat testis

Immunogen:	A synthesized peptide derived from human SAM68
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	10657
Uniprot:	Q07666
Cellular Location:
Calculated MW:	68 kDa
Observed MW:	68KDa

Synonyms:

Sam68, p62, p68

Background:

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

UniProt Protein Function:	KHDRBS1: a nuclear RNA-binding protein. May be involved in slicing and mRNA transport. Associates with src in mitosis. Binds to RNA via a heteronuclear ribonucleoprotein K homology domain. Exerts functionally separable effects on cell proliferation and survival, dependent on its ability to bind specifically to RNA.
UniProt Protein Details:	Protein type:RNA-binding Chromosomal Location of Human Ortholog: 1p32 Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus Molecular Function:identical protein binding; protein binding; SH3/SH2 adaptor activity; DNA binding; RNA binding; protein complex binding; poly(U) binding; SH3 domain binding; poly(A) binding Biological Process: transcription, DNA-dependent; positive regulation of signal transduction; positive regulation of RNA export from nucleus; regulation of protein stability; signal transduction; positive regulation of translational initiation; cell proliferation; cell surface receptor linked signal transduction; regulation of RNA export from nucleus; mRNA processing; cell cycle arrest; G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent
NCBI Summary:	This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
UniProt Code:	Q07666
NCBI GenInfo Identifier:	62511098
NCBI Gene ID:	10657
NCBI Accession:	Q07666.1
UniProt Related Accession:	Q07666
Molecular Weight:	~ 48kDa
NCBI Full Name:	KH domain-containing, RNA-binding, signal transduction-associated protein 1
NCBI Synonym Full Names:	KH RNA binding domain containing, signal transduction associated 1
NCBI Official Symbol:	KHDRBS1
NCBI Official Synonym Symbols:	p62; p68; Sam68
NCBI Protein Information:	KH domain-containing, RNA-binding, signal transduction-associated protein 1
UniProt Protein Name:	KH domain-containing, RNA-binding, signal transduction-associated protein 1
UniProt Synonym Protein Names:	GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68
UniProt Gene Name:	KHDRBS1
UniProt Entry Name:	KHDR1_HUMAN

Western blot - SAM68 Rabbit mAb (CAB3886)

Antibodies

Anti-KHDRBS1 Antibody (CAB6101)

KHDRBS1 Antibody (PACO01469)

KHDRBS1 Antibody (PACO10079)

Secondary Antibody

Anti-HRP Goat Anti-Mouse IgG (H+L) Antibody (CABS003)