159 results for 'CD38'

Key Facts About DaratumumabWhat is Daratumumab?Daratumumab is a monoclonal antibody that targets CD38, a protein highly expressed on the surface of multiple myeloma cells.How does Daratu

The most abundant immunosuppressive molecule in a solid tumour is not a protein. It is adenosine — a metabolite, produced from ATP in two enzymatic steps, at concentrations orders of magnitude above

Immunology · ImmunophenotypingCD Markers on B Cells: Development, Subsets and ImmunophenotypingB cells change their surface marker profile at every stage from bone marrow progenitor to antibody-secret

Imagine a highly trained soldier, elite and effective, sent to the front lines of a relentless war. Day after day, they fight without rest, their supplies dwindle, and the enemy never stops coming. Ev

You can remove almost every B cell from an animal and barely move its antibody titre. That is not a failed experiment — it is the expected result, and it follows from one fact: CD20 is switched off a

B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, play

Transplant rejection is the fastest, most violent adaptive immune response a body can mount — and it is a response to a molecule rather than to a pathogen. Somewhere between one and ten per cent of a

Our Cancer Research Club symposium series continued on Wednesday afternoon, at Royal College of Surgeons (RCSI), Dublin, Ireland. The Bouchier-Hayes lecture theatre was at maximum capacity w

Antigen's are foreign molecules recognised by the immune system. Antigens can be protein, carbohydrate, lipid or nucleic acid molecules. Examples include viruses and bacteria as well as fr

Immunophenotyping by Flow Cytometry Immunophenotyping is a technique used in the field of immunology and cell biology to identify and classify cells based on the specific proteins o

Quick Facts About BelantamabWhat is Belantamab?Belantamab Mafodotin is a cutting-edge antibody-drug conjugate (ADC) designed for the treatment of relapsed or refractory multiple myeloma.

Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells, plasm

Immunology · Innate LymphocytesNatural Killer Cells: Receptors, Subsets and FunctionNK cells kill without prior sensitisation and without antigen-specific receptors, using a balance of activating and