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CD27 Activation: Strengthening the Immune Army Against Cancer(Post)
Harnessing the immune system to fight cancer has become a pivotal strategy in modern oncology. A key component in this fight is CD27, a receptor that plays a crucial role in T-cell activa
Galectin Therapeutics(Post)Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis (IPF) is a chronic, irreversible and ultimately fatal disease characterized by prog
Adhesion molecules in atherosclerosis – ICAM1(Post)Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecules
Inhibiting cell division(Post)Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surrounding
CRISPR-Powered Light Sensors: A New Frontier in Ultra-Sensitive Cancer Detection(Post)Cancer detection often relies on advanced imaging or invasive procedures, frequently catching the disease at later, more challenging stages. Imagine a future where a simple, non-invasive test could s
KO Validated Antibodies(Page)KO Validated Antibodies | Assay Genie
Hijacking the Skull's Gateways: A New 'Backdoor' for Brain Drug Delivery(Post)For decades, the brain has been considered an immune sanctuary, protected by the formidable blood-brain barrier. This intricate defense system, while vital for safeguarding our most complex organ, ha
Metabolic Exhaustion: How Mitochondrial Dysfunction Sabotages CAR-T Cell Therapy in Solid Tumors(Post)Imagine engineering a patient's own immune cells into precision-guided missiles against cancer—cells that can seek out and destroy tumors with remarkable specificity. This is the promise of CAR-T cell
Ce que doit valider tout chercheur sur les anticorps neutralisants(Post)Ce que doit valider tout chercheur sur les anticorps neutralisants Un anticorps neutralisant (AcN) bloque l’infectivité d’un agent pathogène en empêchant l’interaction fonctionnelle avec son récepteu
Psychiatric disorders & LCN2(Post)By Ana Catarina Ferreira, PhD Candidate, Univeristy of Minho, Portugal Psychiatric disorders, including anxiety and depression, are highly prevalent conditio
Dual PD-1/PD-L2 Blockade: Expanding the Horizons of Cancer Immunotherapy(Post)Introduction to PD-1, PD-L1, and PD-L2 in Cancer ImmunotherapyThe PD-1/PD-L1 immune checkpoint pathway has been instrumental in cancer immunotherapy, with PD-1 (programmed death-1) inhibi
COVID-19 Workplace Testing(Post)Workplace Testing for COVID-19 Corporate Testing for COVID-19 The impact of COVID-19 on the econom
cGAS-STING Signalling: Pathway, Regulation and Key Assays(Post)Double-stranded DNA in the cytosol is always a mistake. A virus has uncoated, a mitochondrion has ruptured, a micronucleus has burst, or a chromosome has been broken and left unrepaired. cGAS treats
The Influence of dietary interventions upon platelet reactivity(Post)Laura Menke PhD candidate, Queen Mary University of London Inflammation vs. Resolution Atherothrombosis is the leading cause of death worldwide
Early Diagnosis is key: Pick the weed or allow it destroy the garden?(Post)By Catríona Dowling, Post-Doc, RCSI I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure
NRF2 Signaling: A Keystone in Inflammation and Disease Management(Post)Nuclear Factor Erythroid 2–Related Factor 2 (NRF2) orchestrates a principal defense mechanism against oxidative stress and plays a pivotal role in inflammation and disease pathogenesis. This artic
OX40 Agonists: Revitalizing the Immune Response in Cancer(Post)Cancer immunotherapy has revolutionized treatment options, offering strategies to harness the immune system to target and destroy tumors. One emerging area of interest is the use of OX40
SLAMF7: Activating Natural Killer Cells for Potent Anti-Cancer Responses(Post)Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells, plasm
Immuno-Biomaterial Development | Assay Genie(Post)Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dunn
Secondary Antibodies(Page)Secondary Antibodies | HRP, FITC, Cy3 & AP Conjugates | Assay Genie