The SENP1 Monoclonal Antibody (CAB4460) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting SENP1 in various species, including human samples. Validated for use in Western blot applications, it allows for precise analysis of SENP1 expression levels in different cell types.SENP1, also known as sentrin-specific protease 1, plays a key role in controlling cellular processes such as DNA repair, cell cycle progression, and gene expression by mediating the deSUMOylation of target proteins. Dysfunction of SENP1 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SENP1 Monoclonal Antibody
SKU:
CAB4460
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC1016
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SuPr-2, SENP1
Positive Sample:
HeLa, PC-3
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
73kDa
Observed MW:
73kDa
This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
29843
RRID
AB_2863278
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SENP1 Rabbit mAb (CAB4460) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
