Description
SPIC Transcription Factor Activity Assay
The SPIC Transcription Factor Activity Assay is a powerful tool for researchers studying transcription regulation in various biological pathways. This assay kit offers high sensitivity and specificity, allowing for precise measurements of SPIC transcription factor activity in cells and tissues.SPIC is a key transcription factor that plays a critical role in the regulation of immune responses, inflammation, and cell differentiation. By accurately measuring SPIC activity, researchers can gain valuable insights into the molecular mechanisms underlying these processes.
With its reliable and reproducible results, the SPIC Transcription Factor Activity Assay is suitable for a wide range of experimental settings, making it an essential tool for studying transcriptional regulation and identifying potential therapeutic targets. Trust in this assay kit to deliver accurate and insightful data for your research needs.
| Product Name: | SPIC Transcription Factor Activity Assay |
| Product Code: | TFAB00103 |
| Target: | SPIC |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie SPIC transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | SPIC: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression. Belongs to the ETS family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 12q23.2 Cellular Component: nucleus Biological Process: cell differentiation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016] |
| UniProt Code: | Q8N5J4 |
| NCBI GenInfo Identifier: | 22748707 |
| NCBI Gene ID: | 121599 |
| NCBI Accession: | NP_689536.1 |
| UniProt Related Accession: | Q8N5J4 |
| Molecular Weight: | 29kd |
| NCBI Full Name: | transcription factor Spi-C |
| NCBI Synonym Full Names: | Spi-C transcription factor |
| NCBI Official Symbol: | SPIC |
| NCBI Official Synonym Symbols: | SPI-C |
| NCBI Protein Information: | transcription factor Spi-C |
| UniProt Protein Name: | Transcription factor Spi-C |
| Protein Family: | SpiC |
| UniProt Gene Name: | SPIC |
| UniProt Entry Name: | SPIC_HUMAN |
