Description
T-Cell Exhaustion & Checkpoints Antibody Sampler Pack (ABSP024)
The T-Cell Exhaustion & Checkpoints Antibody Sampler Pack from Assay Genie brings together 6 rigorously validated antibodies covering the key nodes of this pathway in a convenient 20µL trial format. It is designed to let researchers interrogate an entire signalling axis in a single, cost-effective pack, then scale up to full-size formats for the targets that matter most to their work.
| Pack Name: | T-Cell Exhaustion & Checkpoints Antibody Sampler Pack |
| SKU: | ABSP024 |
| Research Area: | Immunology |
| Targets Included: | 6 |
| Format: | 6 × 20µL |
| Targets: | PD-1, PD-L1, CTLA-4, TIM-3, TIGIT, EOMES |
| Target | Antibody | SKU | Host | Reactivity | Applications | Size |
|---|---|---|---|---|---|---|
| PD-1 | Anti-PD-1/CD279 Polyclonal Antibody -Knockout Validated | CAB5584-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
| PD-L1 | Anti-CD274 [ARC61782] Monoclonal Antibody | CAB23922-20 | Rabbit | Mouse | WB ELISA | 20µL |
| CTLA-4 | Anti-CTLA4 Antibody | CAB2063-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| TIM-3 | Anti-TIM-3/HAVCR2 Antibody | CAB13445-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| TIGIT | Anti-TIGIT Antibody | CAB25605-20 | Rabbit | Mouse | WB ELISA | 20µL |
| EOMES | Anti-EOMES Polyclonal Antibody | CAB18222-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
Chronic antigen exposure drives T-cell exhaustion characterised by sustained expression of inhibitory checkpoints PD-1, CTLA-4, LAG-3, TIM-3 and TIGIT and the transcription factors TOX and EOMES. These molecules are central targets of cancer immunotherapy.
| Pack Format: | 6 antibodies, 20µL each (trial size) |
| Storage: | Store at -20°C |
| Shelf Life: | 12 months |
| Shipping: | Gel pack |
Every antibody in this sampler pack is also available individually in full 100µL size for follow-on experiments and assay scale-up.