Description
TBX18 Transcription Factor Activity Assay
The TBX18 Transcription Factor Activity Assay is a cutting-edge research tool designed for the accurate detection of TBX18 transcription factor activity in a variety of cell types. This assay kit features high sensitivity and specificity, allowing for reliable and reproducible results in a wide range of research applications.TBX18 is a key transcription factor involved in various cellular processes, including development and differentiation. It plays a crucial role in regulating gene expression and can impact multiple biological pathways.
Understanding TBX18 activity is essential for studying its role in different diseases and conditions and developing potential therapeutic strategies.The TBX18 Transcription Factor Activity Assay is a valuable tool for researchers investigating the function and regulation of TBX18 in different cellular contexts. With its high sensitivity and specificity, this assay kit provides accurate and precise measurements of TBX18 activity, making it an ideal choice for molecular and cellular biology studies.
| Product Name: | TBX18 Transcription Factor Activity Assay |
| Product Code: | TFAB00168 |
| Target: | TBX18 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie TBX18 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | TBX18: Probable transcriptional regulator involved in developmental processes. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 6q14-q15 Cellular Component: nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent Disease: Huntington Disease |
| NCBI Summary: | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
| UniProt Code: | O95935 |
| NCBI GenInfo Identifier: | 122937456 |
| NCBI Gene ID: | 9096 |
| NCBI Accession: | NP_001073977.1 |
| UniProt Secondary Accession: | O95935,Q7Z6U4, Q9UJI6, A2RU13, |
| UniProt Related Accession: | O95935 |
| Molecular Weight: | 80.8 kDa |
| NCBI Full Name: | T-box transcription factor TBX18 |
| NCBI Synonym Full Names: | T-box 18 |
| NCBI Official Symbol: | TBX18 |
| NCBI Protein Information: | T-box transcription factor TBX18 |
| UniProt Protein Name: | T-box transcription factor TBX18 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | TBX18 |
| UniProt Entry Name: | TBX18_HUMAN |
