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Anti-TRAF6BP/TAX1BP1 Antibody CAB19587
Key Features

TRAF6BP/TAX1BP1 Rabbit Monoclonal Antibody (CAB19587)

Datasheet MSDS
SKU CAB19587
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms T6BP, TXBP151, CALCOCO3, TRAF6BP/TAX1BP1
Research Use Cell Biology
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

TRAF6BP/TAX1BP1 Monoclonal Antibody (CAB19587)

The TRAF6BP/TAX1BP1 Monoclonal Antibody (CAB19587) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.TRAF6BP/TAX1BP1 is involved in multiple cellular processes, including the regulation of NF-kB signaling, autophagy, and inflammation. Dysregulation of TRAF6BP/TAX1BP1 has been implicated in various diseases, such as cancer, autoimmune disorders, and inflammatory conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:TRAF6BP/TAX1BP1 Monoclonal Antibody
SKU:CAB19587
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC2184
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:DSED SKED ENVP TAPD PPSQ HLRG HGTG FCFD SSFD VHKK CPLC ELMF PPNY DQSK FEEH VESH WKVC PMCS EQFP PDYD QQVF ERHV QTHF DQNV LNFD
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:T6BP, TXBP151, CALCOCO3, TRAF6BP/TAX1BP1
Positive Sample:A549, U-937, U-251MG, Mouse testis
Cellular Localization:Cytosol, Extracellular Exosome.
Calculated MW:91kDa
Observed MW:100kDa

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID8887
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TRAF6BP/TAX1BP1 Rabbit mAb (CAB19587) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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