B-Myb Transcription Factor Activity Assay

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TFAB00072
€599

Description

ELISA Kit Technical ManualMSDS

B-Myb Transcription Factor activity assay

Product Description:The ELISA Genie B-Myb transcription factor activity assay Kit components necessary for detection and qualitative analysis of B-Myb active transcription factors in eukaryotic nuclear or cell lysates. ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:Myb-like protein 2
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse, Rat
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

B-Myb Transcription Factor activity assay Protein Information

UniProt Protein Function:B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 20q13.1

Cellular Component: nucleoplasm

Molecular Function:protein binding; chromatin binding; transcription factor activity

Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle

NCBI Summary:The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
UniProt Code:P10244
NCBI GenInfo Identifier:127584
NCBI Gene ID:4605
NCBI Accession:P10244.1
UniProt Secondary Accession:P10244,Q53F07, B2RBS5, B7Z8D9, F8W6N6,
UniProt Related Accession:P10244
Molecular Weight:75,865 Da
NCBI Full Name:Myb-related protein B
NCBI Synonym Full Names:v-myb avian myeloblastosis viral oncogene homolog-like 2
NCBI Official Symbol:MYBL2
NCBI Official Synonym Symbols:BMYB; B-MYB
NCBI Protein Information:myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2
UniProt Protein Name:Myb-related protein B
UniProt Synonym Protein Names:Myb-like protein 2
Protein Family:Myb-related protein
UniProt Gene Name:MYBL2
UniProt Entry Name:MYBB_HUMAN
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