Description
B-Myb Transcription Factor activity assay
Product Description: | The ELISA Genie B-Myb transcription factor activity assay Kit components necessary for detection and qualitative analysis of B-Myb active transcription factors in eukaryotic nuclear or cell lysates. ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening. |
Target Synonyms: | Myb-like protein 2 |
Detection Target: | Phospho-IRAK1(Thr209) |
Reactivity: | Human, Mouse, Rat |
Pack Size: | 12 x 8-Well Microstrips |
Detection Method: | Colorimetric 450 nm |
Format: | transcription factor activity assay |
Storage and Stability Guarantee: | 4°C/6 Months |
Sample Type: | Nuclear or cell lysates |
Range: | See Technical Manual |
Time: | 4.5 hours |
B-Myb Transcription Factor activity assay Protein Information
UniProt Protein Function: | B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 20q13.1 Cellular Component: nucleoplasm Molecular Function:protein binding; chromatin binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle |
NCBI Summary: | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
UniProt Code: | P10244 |
NCBI GenInfo Identifier: | 127584 |
NCBI Gene ID: | 4605 |
NCBI Accession: | P10244.1 |
UniProt Secondary Accession: | P10244,Q53F07, B2RBS5, B7Z8D9, F8W6N6, |
UniProt Related Accession: | P10244 |
Molecular Weight: | 75,865 Da |
NCBI Full Name: | Myb-related protein B |
NCBI Synonym Full Names: | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
NCBI Official Symbol: | MYBL2 |
NCBI Official Synonym Symbols: | BMYB; B-MYB |
NCBI Protein Information: | myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2 |
UniProt Protein Name: | Myb-related protein B |
UniProt Synonym Protein Names: | Myb-like protein 2 |
Protein Family: | Myb-related protein |
UniProt Gene Name: | MYBL2 |
UniProt Entry Name: | MYBB_HUMAN |