Description
Hippo / YAP-TAZ Antibody Sampler Pack (ABSP012)
The Hippo / YAP-TAZ Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies covering the key nodes of this pathway in a convenient 20µL trial format. It is designed to let researchers interrogate an entire signalling axis in a single, cost-effective pack, then scale up to full-size formats for the targets that matter most to their work.
| Pack Name: | Hippo / YAP-TAZ Antibody Sampler Pack |
| SKU: | ABSP012 |
| Research Area: | Cancer |
| Targets Included: | 8 |
| Format: | 8 × 20µL |
| Targets: | YAP, Phospho-YAP, TAZ, LATS1, MST1, MOB1, TEAD1, Merlin/NF2 |
| Target | Antibody | SKU | Host | Reactivity | Applications | Size |
|---|---|---|---|---|---|---|
| YAP | Anti-[KO Validated] YAP1 Monoclonal Antibody | CAB21216-20 | Rabbit | Human, Mouse, Rat | WB IHC-P IF/ICC IP ELISA ChIP | 20µL |
| Phospho-YAP | Anti-Non-phospho-YAP1-S127 Antibody | CAB20250-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| TAZ | Anti-TAZ [ARC57803] Monoclonal Antibody | CAB23034-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
| LATS1 | Anti-LATS1 [ARC56891] Monoclonal Antibody | CAB22287-20 | Rabbit | Human | WB ELISA | 20µL |
| MST1 | Anti-MSP/MST1 Monoclonal Antibody | CAB0109-20 | Rabbit | Human, Mouse, Rat | WB IF-P ELISA | 20µL |
| MOB1 | Anti-MOB1A/B [ARC62859] Monoclonal Antibody | CAB23963-20 | Rabbit | Human Mouse Rat | WB ELISA | 20µL |
| TEAD1 | Anti-TEAD1 [ARC1157] Monoclonal Antibody | CAB5218-20 | Rabbit | Human, Mouse, Rat | WB IP ChIP ELISA CUT&Tag | 20µL |
| Merlin/NF2 | Anti-NF2 Antibody -Knockout Validated | CAB0739-20 | Rabbit | Human, Mouse, Rat | WB IF/ICC IP ELISA | 20µL |
The Hippo pathway restrains organ growth through a MST1/2-LATS1/2 kinase cascade that phosphorylates and inactivates the transcriptional co-activators YAP and TAZ. When Hippo signalling is off, YAP/TAZ enter the nucleus and drive TEAD-dependent proliferation; dysregulation contributes to tumourigenesis and mechanotransduction.
| Pack Format: | 8 antibodies, 20µL each (trial size) |
| Storage: | Store at -20°C |
| Shelf Life: | 12 months |
| Shipping: | Gel pack |
Every antibody in this sampler pack is also available individually in full 100µL size for follow-on experiments and assay scale-up.
