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Human C2CD3 Recombinant Protein (N-GST)
Key Features

Human C2CD3 Recombinant Protein (N-GST) (GXRP02407)

SKU GXRP02407
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-GST
$458 - $2,412

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Description

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Human C2CD3 Recombinant Protein (N-GST)

Human C2CD3 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Asn1432-Leu1647, with an N-terminal GST tag. Predicted molecular weight: 51.22 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. C2 domain-containing protein 3 (C2CD3) is a ~260 kDa protein. Component of the centrioles that acts as a positive regulator of centriole elongation. For research use only.

Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.

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