Description
Human Neuro Discovery Array (20 targets) (SARB0057)
The Human Neuro Discovery Array (SARB0057) is a comprehensive array panel consisting of 20 targets related to neurological research. This array allows for the simultaneous detection and quantification of key proteins involved in various aspects of neurobiology, including neurotransmission, synaptic function, and neuronal development.Utilizing advanced antibody-based detection technology, this array provides researchers with a powerful tool to analyze protein expression levels in complex biological samples. With its high sensitivity and specificity, the Human Neuro Discovery Array enables the identification of potential biomarkers, drug targets, and signaling pathways relevant to neurodegenerative diseases, psychiatric disorders, and neurological conditions.
Designed for use with human samples, this array is suitable for a wide range of applications, including biomarker discovery, drug development, and disease profiling. Whether studying the molecular mechanisms of neurodegeneration or investigating the effects of potential therapeutic interventions, the Human Neuro Discovery Array offers a comprehensive solution for advancing research in neurobiology and neuroscience.
| Product Sku: | SARB0057 |
| Size: | 2, 4, or 8 |
| Species Detected: | Human |
| Number of Targets Detected: | 20 |
| Gene Symbols: | BDNF, CCL2, CCL3, CSF3, CXCL8, GDNF, HBEGF, IFNG, IGF1, IL10|IL1A, IL1B, IL6, MMP2, MMP3, NGF, S100B, TGFB1, TNF, VEGFA |
| Compatible Sample Types: | Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Lysates |
| Design Principle: | Sandwich-based |
| Method of Detection: | Chemiluminescence |
| Pathway: | Akt Signaling |
| Quantitative/Semi-Quantitative: | Semi-Quantitative |
| Solid Support: | Membrane |
| Suggested Application(s): | Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process |
| Storage/Stability: | For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period. Once thawed, store array membranes at -20°C and all other reagents undiluted at 4°C for no more than 3 months. |
| Hover over target for more information | ||||
|---|---|---|---|---|
BDNF
| beta-NGF
| GCSF
| GDNF
| HB-EGF
|
IFN-gamma
| IGF-1
| IL-10
| IL-1 alpha (IL-1 F1)
| IL-1 beta (IL-1 F2)
|
IL-6
| IL-8 (CXCL8)
| MCP-1 (CCL2)
| MIP-1 alpha (CCL3)
| MMP-2
|
MMP-3
| S100 B
| TGF beta 1
| TNF alpha
| VEGF-A
|
- Easy to use
- No specialized equipment needed
- Compatible with nearly any liquid sample
- Proven technology
- Highly sensitive (pg/ml)
- Sandwich ELISA specificity
- Higher density than ELISA, Western blot or bead-based multiplex
- Human Neuro Discovery C1 Membranes
- Blocking Buffer
- Wash Buffer 1
- Wash Buffer 2
- Biotinylated Detection Antibody Cocktail
- Streptavidin-Conjugated HRP
- Detection Buffer C
- Detection Buffer D
- Lysis Buffer
- 8-Well Incubation Tray
- Plastic Sheets
- Array Templates
Other Materials Required
- Pipettors, pipet tips and other common lab consumables
- Orbital shaker or oscillating rocker
- Tissue Paper, blotting paper or chromatography paper
- Adhesive tape or Saran Wrap
- Distilled or de-ionized water
- A chemiluminescent blot documentation system , X-ray Film and a suitable film processor, or another chemiluminescent detection system.
| 1. | Block membranes |
| 2. | Incubate with Sample |
| 3. | Incubate with Biotinylated Detection Antibody Cocktail |
| 4. | Incubate with HRP-Conjugated Streptavidin |
| 5. | Incubate with Detection Buffers |
| 6. | Image with chemiluminescent imaging system |
| 7. | Perform densitometry and analysis |
