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Human RAB28 Recombinant Protein (N-GST)
Key Features

Human RAB28 Recombinant Protein (N-GST) (GXRP01733)

SKU GXRP01733
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-GST
$458 - $2,412

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Description

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Human RAB28 Recombinant Protein (N-GST)

Human RAB28 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Met1-Ile95, with an N-terminal GST tag. Predicted molecular weight: 37.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ras-related protein Rab-28 (RAB28) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. For research use only.

Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina. Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells.

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