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Human TGF beta Array (25 targets) (SARB0070)

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SKU:
SARB0070
Product Type:
Protein Array
Analytes:
Activin A
Activin R1A (ALK-2)
BAMBI (NMA)
beta IG-H3
BMP-2
BMP-4
BMP-6
BMP-7
BMP-8
BMP-9
BMP-15 (GDF-9B)
BMPR-IA (ALK-3)
BMPR-II
Follistatin
GDF-11 (BMP-11)
GDF-15
Lefty-A
Noggin
SMAD3
SMAD4
TGF alpha
TGF beta 1
TGF beta 2
TGF-beta RII
TGF beta R3
Reactivity:
Human
Applications:
Multiplex Array
€649 - €1,269

Description

system_update_altDatasheet

Human TGF beta Array (25 targets) (SARB0070)

The Human TGF-beta Array (SARB0070) offered by Assay Genie is a powerful tool for researchers studying the transforming growth factor beta (TGF-beta) pathway. This array allows for the simultaneous detection of 25 TGF-beta related targets, providing a comprehensive view of the signaling network involved in cell growth, differentiation, and immune response.With high sensitivity and specificity, this array is ideal for analyzing TGF-beta signaling in various cell types and conditions. Researchers can easily track changes in protein expression levels and phosphorylation status, making it an invaluable tool for studies on cancer, fibrosis, and immune regulation.

Validated for use in ELISA and other protein detection assays, the Human TGF-beta Array (SARB0070) offers a cost-effective and time-saving solution for investigating the intricate mechanisms of TGF-beta signaling. Gain deeper insights into the role of TGF-beta in health and disease with this comprehensive array from Assay Genie.

Product Sku:SARB0070
Size:2, 4, or 8
Species Detected:Human
Number of Targets Detected:25
Gene Symbols:ACVR1, BAMBI, BMP15, BMP2, BMP4, BMP6, BMP7, BMP8A, BMPR1A, BMPR2|FST, GDF11, GDF15, GDF2, INHBA, LEFTY2, MADH3, NOG, SMAD4, TGFA, TGFB1, TGFB2, TGFBI, TGFBR2, TGFBR3
Compatible Sample Types:Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Lysates
Design Principle:Sandwich-based
Method of Detection:Chemiluminescence
Pathway:
Quantitative/Semi-Quantitative:Semi-Quantitative
Solid Support:Membrane
Suggested Application(s):Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process
Storage/Stability:For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period.
Once thawed, store array membranes and 1X Blocking Buffer at -20°C and all other reagents undiluted at 4°C for no more than 3 months.
Hover over target for more information
Activin A
  • Gene Symbol: INHBA
  • Gene ID: 3624
  • Accession #: P08476
Activin R1A (ALK-2)
  • Gene Symbol: ACVR1 ACVRLK2
  • Gene ID: 90
  • Accession #: Q04771
BAMBI (NMA)
  • Gene Symbol: BAMBI NMA
  • Gene ID: 25805
  • Accession #: Q13145
beta IG-H3
  • Gene Symbol: TGFBI BIGH3
  • Gene ID: 7045
  • Accession #: Q15582
BMP-2
  • Gene Symbol: BMP2 BMP2A
  • Gene ID: 650
  • Accession #: P12643
BMP-4
  • Gene Symbol: BMP4 BMP2B DVR4
  • Gene ID: 652
  • Accession #: P12644
BMP-6
  • Gene Symbol: BMP6 VGR
  • Gene ID: 654
  • Accession #: P22004
BMP-7
  • Gene Symbol: BMP7 OP1
  • Gene ID: 655
  • Accession #: P18075
BMP-8
  • Gene Symbol: BMP8A
  • Gene ID: 353500
  • Accession #: Q7Z5Y6
BMP-9
  • Gene Symbol: GDF2 BMP9
  • Gene ID: 2658
  • Accession #: Q9UK05
BMP-15 (GDF-9B)
  • Gene Symbol: BMP15 GDF9B
  • Gene ID: 9210
  • Accession #: O95972
BMPR-IA (ALK-3)
  • Gene Symbol: BMPR1A ACVRLK3 ALK3
  • Gene ID: 657
  • Accession #: P36894
BMPR-II
  • Gene Symbol: BMPR2 PPH1
  • Gene ID: 659
  • Accession #: Q13873
Follistatin
  • Gene Symbol: FST
  • Gene ID: 10468
  • Accession #: P19883
GDF-11 (BMP-11)
  • Gene Symbol: GDF11 BMP11
  • Gene ID: 10220
  • Accession #: O95390
GDF-15
  • Gene Symbol: GDF15 MIC1 PDF PLAB PTGFB
  • Gene ID: 9518
  • Accession #: Q99988
Lefty-A
  • Gene Symbol: LEFTY2 EBAF LEFTA LEFTYA TGFB4 PSEC0024
  • Gene ID: 7044
  • Accession #: O00292
Noggin
  • Gene Symbol: NOG
  • Gene ID: 9241
  • Accession #: Q13253
SMAD3
  • Gene Symbol: MADH3 SMAD3
  • Gene ID: 4088
  • Accession #: P84022
SMAD4
  • Gene Symbol: SMAD4 DPC4 MADH4
  • Gene ID: 4089
  • Accession #: Q13485
TGF alpha
  • Gene Symbol: TGFA
  • Gene ID: 7039
  • Accession #: P01135
TGF beta 1
  • Gene Symbol: TGFB1 TGFB
  • Gene ID: 7040
  • Accession #: P01137
TGF beta 2
  • Gene Symbol: TGFB2
  • Gene ID: 7042
  • Accession #: P61812
TGF-beta RII
  • Gene Symbol: TGFBR2
  • Gene ID: N/A
  • Accession #: P37173
TGF beta R3
  • Gene Symbol: TGFBR3
  • Gene ID: 7049
  • Accession #: Q03167
  • Easy to use
  • No specialized equipment needed
  • Compatible with nearly any liquid sample
  • Proven technology
  • Highly sensitive (pg/ml)
  • Sandwich ELISA specificity
  • Higher density than ELISA, Western blot or bead-based multiplex
  • Human TGF beta Array C2 Membranes
  • Blocking Buffer
  • Biotinylated Antibody Cocktail
  • 1,000X HRP-Streptavidin Concentrate
  • 20X Wash Buffer I Concentrate
  • 20X Wash Buffer II Concentrate
  • 2X Cell Lysis Buffer Concentrate
  • Detection Buffer C
  • Detection Buffer D
  • 8-Well Incubation Tray w/ Lid
  • Protease Inhibitor Cocktail
  • Plastic Sheets
  • Array Map Template

Other Materials Required

  • Pipettors, pipet tips and other common lab consumables
  • Orbital shaker or oscillating rocker
  • Tissue Paper, blotting paper or chromatography paper
  • Adhesive tape or Saran Wrap
  • Distilled or de-ionized water
  • A chemiluminescent blot documentation system , X-ray Film and a suitable film processor, or another chemiluminescent detection system.
1.Block membranes
2.Incubate with Sample
3.Incubate with Detection Antibody Cocktail
4.Incubate with HRP-Conjugated anti-IgG
5.Incubate with Detection Buffers
6.Image with chemiluminescent imaging system
7.Perform densitometry and analysis

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