The PE Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) available at Assay Genie is a valuable tool for research involving the Ly6A/E protein in mice. Ly6A/E, also known as Sca-1, is a cell surface marker commonly used in stem cell research and immunology. This antibody, derived from a hybridoma clone D7, is specifically designed to detect and bind to Ly6A/E, allowing for precise analysis and characterization of cells expressing this surface marker.The PE Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) is ideal for flow cytometry applications, enabling researchers to identify and isolate distinct cell populations based on Ly6A/E expression levels. This antibody is rigorously validated for specificity and sensitivity, ensuring reliable and reproducible results in various experimental settings.
By targeting Ly6A/E, researchers can gain insights into stem cell biology, immune cell function, and the role of Ly6A/E-expressing cells in different physiological and pathological processes.With its high specificity and robust performance, the PE Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) is a valuable tool for investigators studying stem cell dynamics, immune cell populations, and tissue regeneration in mouse models. Its versatility and reliability make it a key component in advancing research related to stem cell biology, immunology, and regenerative medicine.
Product Title:
PE Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:
AGEL2346
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
D7
Synonyms:
Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05533
Gene ID:
110454
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
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