The Recombinant CTCFL Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121682) against CTCFL. CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC and FCM applications. It has been validated by WB analysis of HeLa, Jurkat, PC-3, IHC analysis of Human testis, Human skeletal muscle (negative tissue), Mouse testis, Rat testis and FCM analysis of MCF-7, HeLa. The target is localized to the cytoplasm, nucleus.
