The Recombinant IKB epsilon Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310364) against IKB epsilon. The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF, ICC and IP applications. It has been validated by WB analysis of A549. The target is localized to the cytoplasm.
Product Name:
Recombinant IKB epsilon Monoclonal Antibody
SKU:
AGEL5682
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
IKBE, IκB-ε, NFKBIE
Reactivity:
Human
Immunogen:
Recombinant Human IKB epsilon protein
Applications:
WBIHCIFICCIP
Clonality:
Recombinant Monoclonal
Clone No:
C310364
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
IKB epsilon
Conjugation:
Unconjugated
Observed MW:
55 kDa
Recommended Dilution:
WB 1:1000-5000; IHC 1:100-300; ICC/IF 1:100-300; IP 1:50-100
UniProt:
O00221
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.