The Recombinant ING3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131641) against ING3. ING3 is the members of inhibitor of growth (ING) family function in inhibiting cell growth and inducing apoptosis. They are sequence homologous proteins. ING3 can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HeLa,?293T, NIH-3T3, PC-12. The target is localized to the nucleus.
