The Recombinant Keratin 20 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111201) against Keratin 20. Keratin (cytokeratin) is an intermediate filament protein, which is mainly expressed in epithelial cells such as gastric epithelium and intestinal epithelium. Keratin heterodimers composed of acidic keratin (or type I keratin, keratin 9 to 23) and basic keratin (or type II keratin, keratin 1 to 8) assemble to form filaments. Keratin isoforms exhibit tissue- and differentiation-specific characteristics, making them useful as research biomarkers. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and FCM applications. It has been validated by WB analysis of SW480, HCT-116, HT-29, Mouse small intestine, Mouse colon, Rat colon, IHC analysis of Human colon, Human colon cancer, IF analysis of HT-29 and FCM analysis of HT-29. The target is localized to the cytoplasm.
